A miscellaneous collection of letters, mainly of English scientists, written to various people. There are mostly one or two letters, except for those of John Peter Gassiot, William Huggins, Edwin R. Lankester, James Mackintosh, David Prain, and William Whewell.

One of the most important natural historians in nineteenth century Britain, Charles Darwin provided the first compelling mechanism to account for organismal evolutionary change. Although lacking a coherent model of heredity, Darwin's natural selection has exerted an enormous influence over the biological sciences and since the introduction of Mendelian genetics, had remained the key unifying principle in the discipline. The APS Darwin Papers are a large a valuable assemblage of Darwin's correspondence with scientific colleagues, including Charles Lyell and George J. Romanes. They are included in the print version of the Correspondence of Charles Darwin (Cambridge Univ. Press).